EST. 2026 · TOKYO / TALLINN

Institute of One

Institute of One

The First Agentic AI-Native Research Institute in Medical Imaging

The First Agentic AI-Native Research Institute in Medical Imaging

One Human. A Legion of Agents.

One Human. A Legion of Agents.

A research institute of one.

A research institute of one.

One human directs a legion of AI agents to form a working medical-imaging institute — no campus, no department, no borders.

One human directs a legion of AI agents to form a working medical-imaging institute — no campus, no department, no borders.

We publish the process, not only the results.

We publish the process, not only the results.

The prompts, the decisions, the dead ends, the moments a human overrides the machine — all of it is the record. The process is the contribution.

The prompts, the decisions, the dead ends, the moments a human overrides the machine — all of it is the record. The process is the contribution.

Human-accountable. Agent-accelerated.

Human-accountable. Agent-accelerated.

Every output carries one name and one responsibility: a human author. The agents are credited as tools, in the open. Rigor is never traded for speed.

Every output carries one name and one responsibility: a human author. The agents are credited as tools, in the open. Rigor is never traded for speed.

Built in the open, from anywhere.

Built in the open, from anywhere.

Operating across Japan and Estonia, this is a live experiment in what one person and a legion of agents can build.

Operating across Japan and Estonia, this is a live experiment in what one person and a legion of agents can build.

Shuji Yamamoto, PhD — Founder

Medical imaging researcher (PhD, Medical Physics, Osaka University). Three decades across CT, radiomics, and AI-assisted analysis. Visiting researcher, National Cancer Center Japan · Lecturer in medical imaging & AI, Kochi University School of Medicine. RSNA Certificate of Merit; US and Japanese patents. Accountable for everything published here.

ORCID

Google Scholar

ResearchGate

The Fellows are AI agents, not people.

Claude — Chief Research Agent

GPT — Systems Architect

Gemini — Knowledge Analyst

THE LIBRARY

Work is published openly as it happens — Research Notes (IORN), code, and process logs, with DOIs assigned to citable outputs. Everything produced here is a live record of what one person and a legion of agents can build, verify, and share.

Work is published openly as it happens — Research Notes (IORN), code, and process logs, with DOIs assigned to citable outputs. Everything produced here is a live record of what one person and a legion of agents can build, verify, and share.

Institute of One · Supported by Lisit Co., Ltd. (Japan) & TexelCraft OÜ (Estonia) · instituteofone.org